Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 2.361


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
Dmap1 66233 DNA methyltransferase 1-associated protein 1
Ncor1 20185 nuclear receptor co-repressor 1
Ncor2 20602 nuclear receptor co-repressor 2
Smarca1 93761 SWI/SNF related, matrix associated, actin dependent regulator of chromatin,
Smarca5 93762 SWI/SNF related, matrix associated, actin dependent regulator of chromatin,
Smarcc2 68094 SWI/SNF related, matrix associated, actin dependent regulator of chromatin,

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smarca1chrX_-_45245608-0.531.3e-14Click!
Ncor2chr5_-_125659422-0.312.4e-05Click!
Smarca5chr8_-_832628810.231.9e-03Click!
Dmap1chr4_-_1173548290.223.2e-03Click!
Ncor1chr11_-_62206116-0.181.6e-02Click!
Smarcc2chr10_+_127896244-0.163.4e-02Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_9046362 53.819 NM_007807
Cybb
cytochrome b-245, beta polypeptide
chr7_-_128217980 52.800 NM_030691
Igsf6
immunoglobulin superfamily, member 6
chr11_+_33946927 51.928 Lcp2
lymphocyte cytosolic protein 2
chr4_-_133650937 51.069 NM_013706
Cd52
CD52 antigen
chr6_-_129422702 48.081 NM_020008
Clec7a
C-type lectin domain family 7, member a
chr6_-_16848352 46.555 NM_031198
Tcfec
transcription factor EC
chr3_+_95330700 43.055 NM_021281
Ctss
cathepsin S
chr6_-_16848314 42.411 Tcfec
transcription factor EC
chr9_+_5298516 41.341 NM_009807
Casp1
caspase 1
chr8_+_90818102 40.981 NM_001037724
Adcy7
adenylate cyclase 7
chr5_-_134705423 34.796 NM_010876
Ncf1
neutrophil cytosolic factor 1
chr4_-_155574875 34.597 NM_015783
Isg15
ISG15 ubiquitin-like modifier
chr11_+_33947115 33.209 NM_010696
Lcp2
lymphocyte cytosolic protein 2
chr1_-_146096156 30.919 NM_015811
Rgs1
regulator of G-protein signaling 1
chr11_-_83343962 30.912 NM_013653
Ccl5
chemokine (C-C motif) ligand 5
chrX_+_83115611 30.654 NM_001163539
5430427O19Rik
RIKEN cDNA 5430427O19 gene
chr7_+_86058817 30.334 Isg20
interferon-stimulated protein
chr4_+_144482722 29.897 NM_001172424
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr12_-_32893074 29.231 NM_001146201
NM_020272
NM_001146200
Pik3cg


phosphoinositide-3-kinase, catalytic, gamma polypeptide


chr16_+_35939047 29.093 Parp9
poly (ADP-ribose) polymerase family, member 9

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 129 entries
Enrichment   P-value GO Accession GO Term
5.19 3.58e-02 GO:0045582 positive regulation of T cell differentiation
4.92 2.32e-02 GO:0045621 positive regulation of lymphocyte differentiation
4.51 1.97e-03 GO:0048660 regulation of smooth muscle cell proliferation
4.47 7.96e-05 GO:0050870 positive regulation of T cell activation
3.94 1.16e-02 GO:0002819 regulation of adaptive immune response
3.80 3.57e-02 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
3.59 4.28e-04 GO:0051251 positive regulation of lymphocyte activation
3.39 1.15e-03 GO:0050863 regulation of T cell activation
3.30 1.84e-03 GO:0002696 positive regulation of leukocyte activation
3.29 1.94e-02 GO:0030098 lymphocyte differentiation
3.18 3.58e-03 GO:0050867 positive regulation of cell activation
3.14 2.14e-02 GO:0001819 positive regulation of cytokine production
2.98 9.22e-04 GO:0051249 regulation of lymphocyte activation
2.97 3.06e-02 GO:0002252 immune effector process
2.76 2.79e-03 GO:0002694 regulation of leukocyte activation
2.76 6.39e-03 GO:0046649 lymphocyte activation
2.72 4.76e-02 GO:0051223 regulation of protein transport
2.64 6.44e-03 GO:0050865 regulation of cell activation
2.63 1.87e-04 GO:0051707 response to other organism
2.62 2.53e-02 GO:0030036 actin cytoskeleton organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
Enrichment   P-value GO Accession GO Term
2.79 4.03e-02 GO:0016604 nuclear body
1.96 3.81e-04 GO:0044451 nucleoplasm part
1.77 3.30e-04 GO:0005654 nucleoplasm
1.62 2.54e-05 GO:0044428 nuclear part
1.62 3.41e-04 GO:0005829 cytosol
1.60 8.12e-04 GO:0031981 nuclear lumen
1.50 3.51e-13 GO:0005634 nucleus
1.47 2.93e-05 GO:0043234 protein complex
1.47 1.24e-02 GO:0031974 membrane-enclosed lumen
1.47 1.31e-02 GO:0070013 intracellular organelle lumen
1.47 1.41e-02 GO:0043233 organelle lumen
1.41 6.15e-05 GO:0032991 macromolecular complex
1.37 2.19e-05 GO:0044422 organelle part
1.37 2.45e-05 GO:0044446 intracellular organelle part
1.37 2.17e-02 GO:0043228 non-membrane-bounded organelle
1.37 2.17e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.32 9.00e-12 GO:0043227 membrane-bounded organelle
1.31 1.75e-11 GO:0043231 intracellular membrane-bounded organelle
1.30 4.11e-13 GO:0043226 organelle
1.30 6.70e-13 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
3.21 2.40e-05 GO:0043566 structure-specific DNA binding
2.91 2.20e-02 GO:0003690 double-stranded DNA binding
2.49 2.34e-04 GO:0016563 transcription activator activity
2.29 7.92e-03 GO:0008134 transcription factor binding
2.27 5.12e-07 GO:0043565 sequence-specific DNA binding
2.26 1.02e-02 GO:0016564 transcription repressor activity
2.11 8.11e-08 GO:0030528 transcription regulator activity
2.06 1.07e-05 GO:0001071 nucleic acid binding transcription factor activity
2.06 1.07e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.86 2.30e-10 GO:0003677 DNA binding
1.73 4.48e-02 GO:0003723 RNA binding
1.69 1.06e-10 GO:0003676 nucleic acid binding
1.63 1.00e-03 GO:0008270 zinc ion binding
1.56 1.09e-03 GO:0046914 transition metal ion binding
1.47 4.29e-14 GO:0005515 protein binding
1.27 3.27e-14 GO:0005488 binding